


Quality products make an important contribution to long-term revenue and profitability. Top Quality Chinese Manufacturer supply 75921-69-6 Melanotan-1
[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt has been used to detect its effect on O2 consumption and CO2 production in C57BL/6 mice.1It is also used to determine its effect on leptin secretion in the primary cultures of differentiated adipocytes.
N-(fluoren-9-ylmethoxycarbonyl)glycine
Fmoc-Val-OH
Fmoc-Pro-OH
Fmoc-Ser(tBu)-OH
(S)-2-[{({9H-fluoren-9-yl}methoxy)carbonyl}amino]pentanedioic acid
Fmoc-Tyr(tBu)-OH
Fmoc-Lys-OH
Fmoc-D-Phe-OH
Fmoc-His(Trt)-OH
Fmoc-(S)-2-aminohexanoic acid
3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine
NDP-MSH
| Conditions | Yield |
|---|---|
|
Fmoc-Val-OH;
With
6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
for 0.5h;
With
piperidine;
In
N,N-dimethyl-formamide;
for 0.333333h;
N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Pro-OH; Fmoc-Ser(tBu)-OH; (S)-2-[{({9H-fluoren-9-yl}methoxy)carbonyl}amino]pentanedioic acid; Fmoc-Tyr(tBu)-OH; Fmoc-Lys-OH; Fmoc-D-Phe-OH; Fmoc-His(Trt)-OH; Fmoc-(S)-2-aminohexanoic acid; 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester; Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine;
Further stages;
|
NDP-MSH
[125I]2,3,5,6-tetrafluorophenyl 4-fluoro-3-iodobenzoate
[125I][Nle4, D-Phe7, FIB-Lys11]α-MSH
| Conditions | Yield |
|---|---|
|
With
borate buffer;
In
acetonitrile;
at 45 ℃;
for 0.5h;
pH=8;
|
The CAS number of Melanotan-1 is 75921-69-6.
More information of Melanotan-1 75921-69-6 are:
|
CAS Number |
75921-69-6 |
|
Density |
1.46 g/cm3 |
|
Refractive Index |
1.674 |
|
PSA |
642.98000 |
|
LogP |
3.12050 |
|
Pka |
4.43±0.10(Predicted) |
Synonyms for Melanotan-1 75921-69-6:alpha-Msh, nle(4)-phe(7)-;alpha-Msh, norleucyl(4)-D-phenylalanyl(7)-;(Nle4,D-Phe7)-alpha-MSH;Afamelanotide;Msh, 4-norleucyl-7-phenylalanine-alpha-;(Nle4-D-Phe7)-alpha-Melanocyte-stimulating hormone;alpha-Melanotropin, 4-L-norleucine-7-D-phenylalanine-;
The chemical formula of Melanotan-1 is C78H111N21O19 which containing 78 Carbon atoms,111 Hydrogen atoms,21 Nitrogen atoms and 19 Oxygen atoms,and the molecular weight of Melanotan-1 is 1646.87.
Melanotan-1 is a synthetic peptide hormone that is a modified version of α-Melanocyte Stimulating Hormone (α-MSH). It is designed to increase melanin production in the skin, which provides a natural tan and protects against harmful UV radiation.
InChI:InChI=1/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61-,62-,65-/m0/s1
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