


InChI:InChI=1/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)
The present invention relates to novel c...
The invention provides a method for prep...
A new synthetic route to the Dow AgroSci...
The N-arylsulfilimine-catalyzed coupling...
5,7-dimethoxy-[1,2,4]-triazolo-[1,5-a]-pyrimidin-2-amine
2-methoxy-4-(trifluoromethyl)-pyridine-3-sulfonyl chloride
pyroxsulam
| Conditions | Yield |
|---|---|
|
5,7-dimethoxy-[1,2,4]-triazolo-[1,5-a]-pyrimidin-2-amine; 2-methoxy-4-(trifluoromethyl)-pyridine-3-sulfonyl chloride;
With
dmap;
In
dichloromethane;
for 0.5h;
With
triethylamine;
In
dichloromethane;
at 20 - 35 ℃;
for 3h;
Temperature;
|
94% |
|
With
3,5-Lutidine; dimethyl sulfoxide;
In
acetonitrile;
at 20 ℃;
for 12h;
Product distribution / selectivity;
|
82% |
|
With
3,5-Lutidine;
N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-S,S-dimethyl-sulfilimine hydrochloride salt;
In
acetonitrile;
at 20 ℃;
for 22h;
Product distribution / selectivity;
|
78% |
|
With
3,5-Lutidine;
In
dimethyl sulfoxide; acetonitrile;
at 25 ℃;
for 16h;
Reagent/catalyst;
Inert atmosphere;
|
C15H13F3N6O7S
pyroxsulam
| Conditions | Yield |
|---|---|
|
In
toluene; acetonitrile;
at 20 - 35 ℃;
Inert atmosphere;
|
83% |
5,7-dimethoxy-[1,2,4]-triazolo-[1,5-a]-pyrimidin-2-amine
2-methoxy-4-(trifluoromethyl)-pyridine-3-sulfonyl chloride