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Urea-containing preparations have a softening and moisturizing effect on the stratum corneum and, at times, may provide good therapy for dry skin and the pruritus associated with it. They appear to have an antipruritic effect apart from their hydrating qualities. Urea compounds disrupt the normal hydrogen bonds of epidermal proteins; therefore, their effect in dry hyperkeratotic diseases such as ichthyosis vulgaris and psoriasis is not only to make the skin more pliable but also to help remove adherent scales. Lactic acid also has a softening and moisturizing effect on the stratum corneum.Urea 40% ointment may be useful in removing hypertrophic or dystrophic psoriatic nails. Subsequent topical therapy to the denuded nail bed and proximal nail fold may result in regrowth of ‘‘normal’’ nails in half of those treated.
1) UREA, FCC is an odorless and colorless solid that is an important nitrogen-containing substance found in mammal urine.2) Urea has little or no nutritional value to monogastric mammals but Urea is used in sugar-free chewing gum to adjust the texture
methylenediurea
(hydroxymethyl)urea
urea
| Conditions | Yield |
|---|---|
|
In
sulfuric acid;
at 343 ℃;
Rate constant;
|
methylenediurea
water
(hydroxymethyl)urea
urea
| Conditions | Yield |
|---|---|
|
at 40 - 60 ℃;
Rate constant;
in Loesungen von pH 2.9 bis pH 4.87.Hydrolysis;
|
The CAS number of Urea is 57-13-6.
More information of Urea 57-13-6 are:
|
CAS Number |
57-13-6 |
|
Density |
1.32 g/cm3 |
|
Melting Point |
131-135 °C |
|
Boiling Point |
196.611 °C at 760 mmHg |
|
Flash Point |
72.708 °C |
|
Vapor Pressure |
<0.1 hPa (20 °C) |
|
Refractive Index |
n20/D 1.40 |
|
HS CODE |
31021010 |
|
PSA |
69.11000 |
|
LogP |
0.42440 |
|
Pka |
0.10(at 25℃) |
Synonyms for Urea 57-13-6:Carbamide;Carbonyl diamide;Carbonyldiamine;Diaminomethanal;Diaminomethanone;Prespersion, 75 urea;Urea-13C;Ureacin-20;Urepearl;
The chemical formula of Urea is CH4N2O which containing 1 Carbon atoms,4 Hydrogen atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of Urea is 60.0556.
Urea is a stable highly water-soluble compound of high nitrogen content (47%), with good storage properties that make it the most commonly used nitrogen fertilizer. The synthesis process has remained essentially unchanged since it was first developed by the BASF Corporation in 1922. In this process, liquid ammonia is reacted with carbon dioxide to produce ammonium carbamate, which is then dehydrated to form urea. The reactions are: 2NH3 + CO2 ===? NH2·CO2·NH4 NH2·CO2·NH4 ===? (NH2)2CO + H2O
InChI:InChI=1/CH4N2O/c2-1(3)4/h(H4,2,3,4)
Relevant articles related to Urea:
|
Article |
Source |
|
- |
Walker,Kay , p. 489 (1897) |
|
Oxidation of Thiourea by Aqueous Bromine: Autocatalysis by Bromide |
Simoyi, Reuben H.,Epstein, Irving R. , p. 5124 - 5128 (1987) |
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